Former Chelsea forward Borini added a third early in the second half of the game before Barcelona loanee Bojan Krkic put the game beyond any doubt in the dying minutes of the match.
Serie A leaders Juventus were held to a 0-0 home draw against relegation-threatened Siena.
Second-placed AC Milan could not find a way past a stubborn Napoli side in another goalless stalemate.
In bad news for Milan, Zlatan Ibrahimovic was sent off for a petulant slap on Salvatore Aronica.
Udinese missed a chance to join AC Milan on points after they lost 3-2 at Fiorentina, despite taking the lead.
Antonio Di Natale's early strike was cancelled out by a Stevan Jovetic penalty and the Montenegro international was to score from the spot again in the second half.
Mattia Cassani also netted for Fiorentina and they held on for all three points despite Romanian Gabriel Torje's late consolation.
In other matches, Bosko Jankovic bagged a double for Genoa as they beat a 10-man Lazio 3-2.
Parma won 2-1 at Chievo.
While, matches between Lecce and Bologna, and Novara and Cagliari, ended without a goal.
Match Cesena's home game with Catania on Saturday have both been postponed because of the snow and cold weather gripping Italy.
