Fabio Borini scored the only goal of the contest inside three minutes to send the capital outfit on their way to all three points at the Stadio Renzo Barbera, which vaults them over Inter into sixth place in the Serie A standings.
AC Milan moved four points clear at the top of Serie A on Sunday with a 2-0 win over Lecce.
Antonio Nocerino's deflected effort put hosts Milan ahead inside seven minutes at the San Siro after a neat flick from Zlatan Ibrahimovic.
Swede Ibrahimovic then turned goal scorer after half-time with his fierce volley from Robinho's knock down giving Massimo Benassi no chance in the Lecce goal.
Juventus' goalless draw at Genoa was a baffling result given the visitors hit the bar three times.
Francesco Lodi scored from the penalty spot shortly before the hour mark to lift Catania to a 1-0 win over Fiorentina at Stadio Angelo Massimino.
Gabriel Paletta's goal for Parma cancelled out Tomas Manfredini's fourth-minute opener in a 1-1 draw with Atalanta.
A controversial Luca Ceccarelli red card proved the turning point as relegation-threatened Cesena conceded two late goals in a 2-0 loss to Siena.
Ceccarelli slid in on Siena's Emanuele Calaio in the box, drawing a penalty and a red card.
Claudio Terzi's penalty was pushed on to the upright but Franco Brienza tapped in the rebound, seemingly from an offside position.
Erjon Bogdani sealed the three points, scoring against his former side with a volley from Brienza's delightful pass.
Bologna surprised third-placed Lazio with a 3-1 win away from home.
Daniele Portanova, Alessandro Diamantia and Rene Krhin were all on target for the visitors at the Stadio Olimpico.
Promoted side Novara, second from bottom on the table, scored an upset 1-0 win at home to fifth-placed Udinese.
